Lapse in Institutional Animal Care and Use Committee Continuing Reviews

نویسندگان

  • Min-Fu Tsan
  • Michael Grabenbauer
  • Yen Nguyen
چکیده

The United States federal animal welfare regulations and the Public Health Service Policy on Humane Care and Use of Laboratory Animals require that institutional animal care and use committees (IACUCs) conduct continuing reviews of all animal research activities. However, little is known about the lapse rate of IACUC continuing reviews, and how frequently investigators continue research activities during the lapse. It is also not clear what factors may contribute to an institution's lapse in IACUC continuing reviews. As part of the quality assurance program, the Department of Veterans Affairs (VA) has collected performance metric data for animal care and use programs since 2011. We analyzed IACUC continuing review performance data at 74-75 VA research facilities from 2011 through 2015. The IACUC continuing review lapse rates improved from 5.6% in 2011 to 2.7% in 2015. The rate of investigators continuing research activities during the lapse also decreased from 47.2% in 2012 to 7.4% in 2015. The type of IACUCs used and the size of animal research programs appeared to have no effect in facility's rates of lapse in IACUC continuing reviews. While approximately 80% of facilities reported no lapse in IACUC continuing reviews, approximately 14% of facilities had lapse rates of >10% each year. Some facilities appeared to be repeat offenders. Four facilities had IACUC lapse rates of >10% in at least 3 out of 5 years, suggesting a system problem in these facilities requiring remedial actions to improve their IACUC continuing review processes.

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منابع مشابه

Institutional Animal Care and Use Committee (IACUC)

Institutional Animal Care and Use Committee (IACUC) Amendments & Protocols Access to the Amendments & Protocols Online System [1] Instructions for submitting protocols and amendments [2] Protocol Template Form (doc [3], docx [4]) [5] VMTH Clinical Trials [6] [7] ACU 101 Online Course [8] Animal Care and Use Courses [9] ApplicationOccupational Health and Animals (OHSS) [10] Animal Tracking Syste...

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Institutional Animal Care and Use Committee (IACUC)

Institutional Animal Care and Use Committee (IACUC) Amendments & Protocols Access to the Amendments & Protocols Online System [1] Instructions for submitting protocols and amendments [2] Protocol Template Form (doc [3], docx [4]) [5] VMTH Clinical Trials [6] [7] ACU 101 Online Course [8] Animal Care and Use Courses [9] ApplicationOccupational Health and Animals (OHSS) [10] Animal Tracking Syste...

متن کامل

Institutional Animal Care and Use Committee (IACUC)

Institutional Animal Care and Use Committee (IACUC) Amendments & Protocols Access to the Amendments & Protocols Online System [1] Instructions for submitting protocols and amendments [2] Protocol Template Form (doc [3], docx [4]) [5] VMTH Clinical Trials [6] [7] ACU 101 Online Course [8] Animal Care and Use Courses [9] ApplicationOccupational Health and Animals (OHSS) [10] Animal Tracking Syste...

متن کامل

Institutional Animal Care and Use Committee (IACUC)

Institutional Animal Care and Use Committee (IACUC) Amendments & Protocols Access to the Amendments & Protocols Online System [1] Instructions for submitting protocols and amendments [2] Protocol Template Form (doc [3], docx [4]) [5] VMTH Clinical Trials [6] [7] ACU 101 Online Course [8] Animal Care and Use Courses [9] ApplicationOccupational Health and Animals (OHSS) [10] Animal Tracking Syste...

متن کامل

Institutional Animal Care and Use Committee (IACUC)

Institutional Animal Care and Use Committee (IACUC) Amendments & Protocols Access to the Amendments & Protocols Online System [1] Instructions for submitting protocols and amendments [2] Protocol Template Form (doc [3], docx [4]) [5] VMTH Clinical Trials [6] [7] ACU 101 Online Course [8] Animal Care and Use Courses [9] ApplicationOccupational Health and Animals (OHSS) [10] Animal Tracking Syste...

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عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2016